COVID Vaccine !

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Pale Rider

Legendary Member
I recall we have a wager on UK vs Germany death rates.

https://www.cyclechat.net/threads/why-i-voted-for-brexit.271529/page-28#post-6304384

I think Paddy Power would already have paid up.

UK daily case rates 6,000 and falling, Germany daily case rates 9,000 and rising.

I think Paddy will be keeping his powder dry for a while longer.
 

Ajax Bay

Guru
Location
East Devon
The whole health incidents after an Oxford-AZ jab seems to be very well reported Europe (plus Norway)-wide.
https://www.rte.ie/news/coronavirus/2021/0307/1201536-astrazeneca-inquiry/
Should we assume that there have been no such incidents in UK (where more Ox-AZ doses have been given than the rest of world combined (assumed)) or are such adverse reaction event notification reporting being supressed here?
I expect the stats will show that the adverse events following immunisation (AEFIs) experienced are typical of the (normalised) population and no causal link with vaccination will be established. Perfectly reasonable to take a precautionary approach. There is a risk, though, that loud/unblanced reporting will undermine vaccine confidence/uptake.
In parallel, are we to assume that there have been no adverse incidents with other vaccines eg Pfizer-BioNTech across the world (Israel/USA/EU)? Or is this an EU 'B'ehavioural or anti-AZ recrimination issue?
https://www.euractiv.com/section/co...azeneca-covid-shots-after-blood-clot-reports/
[ETA]
"More than 11 million doses of AstraZeneca’s vaccine have so far been administered across the UK.
"In a statement, AstraZeneca said it had found no evidence of an increased risk of pulmonary embolism or deep vein thrombosis in safety data of more than 10 million records, even when considering subgroups based on age, gender, production batch or country of use.
""In fact, the observed number of these types of events are significantly lower in those vaccinated than what would be expected among the general population,” it added."
 
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vickster

Legendary Member
What’s the incidence of blood clots in Covid patients?
Friend of mine, Consultant anaesthetist in large tertiary referral centre says she’s seen a number of cases of Covid clots leading to limb amputation in young patients :thumbsdown:
it can be a very nasty disease even if it doesn’t kill you :sad:
 
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PK99

Legendary Member
Location
SW19
The UK has given over 10 million doses of both the Oxford and Pfizer vaccine. Number of blood clot related events: Oxford = 13 Pfizer = 15 These numbers are no higher than what is seen in the general population (no increased risk).

I had a dvt a few years ago.

Risk factors: male, 6ft and over 60

Turned out I know a goodly number of blokes my age who have had a DVT, it is MUCH more common than I would ever have thought.

Across the population it is 1 in 1000 per year
 

Buck

Guru
Location
Yorkshire
The whole health incidents after an Oxford-AZ jab seems to be very well reported Europe (plus Norway)-wide.
https://www.rte.ie/news/coronavirus/2021/0307/1201536-astrazeneca-inquiry/
Should we assume that there have been no such incidents in UK (where more Ox-AZ doses have been given than the rest of world combined (assumed)) or are such adverse reaction event notification reporting being supressed here?
I expect the stats will show that the adverse events following immunisation (AEFIs) experienced are typical of the (normalised) population and no causal link with vaccination will be established. Perfectly reasonable to take a precautionary approach. There is a risk, though, that loud/unblanced reporting will undermine vaccine confidence/uptake.
In parallel, are we to assume that there have been no adverse incidents with other vaccines eg Pfizer-BioNTech across the world (Israel/USA/EU)? Or is this an EU 'B'ehavioural or anti-AZ recrimination issue?
https://www.euractiv.com/section/co...azeneca-covid-shots-after-blood-clot-reports/
[ETA]
"More than 11 million doses of AstraZeneca’s vaccine have so far been administered across the UK.
"In a statement, AstraZeneca said it had found no evidence of an increased risk of pulmonary embolism or deep vein thrombosis in safety data of more than 10 million records, even when considering subgroups based on age, gender, production batch or country of use.
""In fact, the observed number of these types of events are significantly lower in those vaccinated than what would be expected among the general population,” it added."

all incidents should be reported by the patient or clinician using the MHRA Yellow Card scheme and this is actively encouraged via https://coronavirus-yellowcard.mhra.gov.uk/

There have been a relatively small number of incidents (not just clots). Out of the thousands that we have administered we have had literally just a handful of patients who have felt feint (the majority of whom were already predisposed to such events) and zero adverse reactions in clinic or reported afterwards.

The vaccine related thrombosis is reported to us as 1 in 136,000 which is lower than the natural incidence.
 

houblon

Senior Member
Friend of mine, Consultant anaesthetist in large tertiary referral centre says she’s seen a number of cases of Covid clots...
The UK has given over 10 million doses of both the Oxford and Pfizer vaccine. Number of blood clot related events: Oxford = 13 Pfizer = 15 These numbers are no higher than what is seen in the general population (no increased risk).

Unfortunately the anecdote will have got halfway round the world before the statistic has got its shoes on
 

classic33

Leg End Member
all incidents should be reported by the patient or clinician using the MHRA Yellow Card scheme and this is actively encouraged via https://coronavirus-yellowcard.mhra.gov.uk/

There have been a relatively small number of incidents (not just clots). Out of the thousands that we have administered we have had literally just a handful of patients who have felt feint (the majority of whom were already predisposed to such events) and zero adverse reactions in clinic or reported afterwards.

The vaccine related thrombosis is reported to us as 1 in 136,000 which is lower than the natural incidence.
Well I got to spend four hours in the local A&E, via ambulance from the vaccination centre. Having been given the safer of two currently in use.

Wondering now if the second would result in similar results.

Constant bombardment with text message's about it, and the importance of being part of the program, got me P'd off. Six a day since the appointment was confirmed.
 

Ajax Bay

Guru
Location
East Devon
@Buck - thank you. To be clear I was using the verb 'reporting' in a public media sense. Ch8 of the Green Book is very clear on adverse reaction event notification reporting - and I'm sure it's being done/followed with extra care during this vaccination programme.
@dodgy - thank you for the stats. The supply split between the two vaccines was about 50/50% - statistically the same as the blood clot split.
As @vickster says, press reporting of isolated adverse events cannot but hinder vaccine acceptance in populations ready to hear 'why not'. Macron's 'quasi-ineffective' remark (and others' less egregious behaviours) will have cost many European lives.
Second dose in a hospital setting @classic33 ? Clap on the back though! Bravo!
 

classic33

Leg End Member
@Buck - thank you. To be clear I was using the verb 'reporting' in a public media sense. Ch8 of the Green Book is very clear on adverse reaction event notification reporting - and I'm sure it's being done/followed with extra care during this vaccination programme.
@dodgy - thank you for the stats. The supply split between the two vaccines was about 50/50% - statistically the same as the blood clot split.
As @vickster says, press reporting of isolated adverse events cannot but hinder vaccine acceptance in populations ready to hear 'why not'. Macron's 'quasi-ineffective' remark (and others' less egregious behaviours) will have cost many European lives.
Second dose in a hospital setting @classic33 ? Clap on the back though! Bravo!
Clap on the back for what. Being put into A&E as a result?
 
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