COVID Vaccine !

[SpokeyDokey]

Please correct me if I'm wrong.

I'm sure that JVT said the other day that with the Oxford vaccine, during trials, that no one has had to be hospitalised after the first jab apart from two persons who already had the virus prior to inoculation.

If that's the case then the delay re second jab seems relatively low risk.

 

[Rocky]

Please correct me if I'm wrong.

I'm sure that JVT said the other day that with the Oxford vaccine, during trials, that no one has had to be hospitalised after the first jab apart from two persons who already had the virus prior to inoculation.

If that's the case then the delay re second jab seems relatively low risk.

I think you are right - I think the main issue is how long was the period between the two jabs in the clinical trials, whose data was submitted to the MHRA when they sought approval for the vaccine. In fact the Prof (my wife) tells me that a gap of 12 weeks gives the maximum immune response. I'm not sure if all the trials (for the different vaccines) show this.

So the main argument now against the change of plan, is that there are 900,000 people vaccinated with one jab who are expecting to get a second jab in the next 10 days.....and they'll no longer get one. Contacting them is going to make a lot of extra work for someone. Clinically, however, the delay seems to be a positive move and it will mean an extra 900,000 will get their first dose sooner.

 

[C R]

I think you are right - I think the main issue is how long was the period between the two jabs in the clinical trials, whose data was submitted to the MHRA when they sought approval for the vaccine. In fact the Prof (my wife) tells me that a gap of 12 weeks gives the maximum immune response. I'm not sure if all the trials (for the different vaccines) show this.

So the main argument now against the change of plan, is that there are 900,000 people vaccinated with one jab who are expecting to get a second jab in the next 10 days.....and they'll no longer get one. Contacting them is going to make a lot of extra work for someone. Clinically, however, the delay seems to be a positive move and it will mean an extra 900,000 will get their first dose sooner.

How was that optimal 12 week period determined, was that done separately from the phase 3 study used for the vaccine authorisation?

 

[Rocky]

How was that optimal 12 week period determined, was that done separately from the phase 3 study used for the vaccine authorisation?

I don’t know that I’m sorry. I’ve seen references to it in the FT and Times. I’m not on Twitter but the Prof tells me that a number of medical tweeters also have made the claim. If I find any stronger evidence then I’ll post a link.

I’m guessing in amongst the trial data, there is a subset of patients who were dosed with a 12 week gap although the majority had a shorter gap. It’s fascinating this stuff - isn’t it? Unless you are a confused 88 year old trying to work out when you next have an injection

 

[brodiej]

GPs Some CC members have received their 1st dose; I'd be interested to hear how they feel about this.

I had my 1st dose on December 22nd and was due my 2nd on January 13th

I’m in the clinically extremely vulnerable group put in a Tier 4 area on Boxing Day so am having to shield.

I’m a doctor on the front line who was looking after COVID patients even up to Christmas Eve.

I don’t think people realise how bad the situation is in hospitals right now - it’s terrifying. With the new variant I don’t think even a full lockdown including schools would be enough to hold it. The vaccine needs to be given out as quickly as possible just to try to control the R number.

I don’t think they have a lot of choice other than to go with getting as many people their 1st dose ASAP. The new variant has changed everything and it’s out of control.

On a personal level I’ve got no idea what to do or what I’ll be advised. I’ve been told I have to work from home until 1 week after my 2nd dose. If that still stands I could be working from home for 12 weeks which would seem a bit ridiculous given the shortage of front line medics.

I wouldn’t be surprised if they find a way to give 2nd doses to shielding front line staff

 

[Fab Foodie]

I remember when ‘getting a dose’ was a bad thing....

 

[IaninSheffield]

I had my 1st dose on December 22nd and was due my 2nd on January 13th

I’m in the clinically extremely vulnerable group put in a Tier 4 area on Boxing Day so am having to shield.

I’m a doctor on the front line who was looking after COVID patients even up to Christmas Eve.

I don’t think people realise how bad the situation is in hospitals right now - it’s terrifying. With the new variant I don’t think even a full lockdown including schools would be enough to hold it. The vaccine needs to be given out as quickly as possible just to try to control the R number.

I don’t think they have a lot of choice other than to go with getting as many people their 1st dose ASAP. The new variant has changed everything and it’s out of control.

On a personal level I’ve got no idea what to do or what I’ll be advised. I’ve been told I have to work from home until 1 week after my 2nd dose. If that still stands I could be working from home for 12 weeks which would seem a bit ridiculous given the shortage of front line medics.

I wouldn’t be surprised if they find a way to give 2nd doses to shielding front line staff

Thank you for your reply and setting out the situation so plainly. More importantly, thank you for what you have done, are doing and will do in the coming weeks and months. Please can I wish you well, both in your profession and personally in the year ahead.

 

[srw]

Is that because you are 14?

I'm 36 years older than 14, so I'm actually on the list, and it's telling me I'll be somewhere between December 2021 and January 2022. I'd guess that everyone not on the list will be told January to June 2022.

 

[Rocky]

I'm 36 years older than 14, so I'm actually on the list, and it's telling me I'll be somewhere between December 2021 and January 2022. I'd guess that everyone not on the list will be told January to June 2022.

I’m 64, the Prof is 61. Originally we’d thought we might get something in Feb but our gestimate now is April-May at the earliest. I thought we might get mates rates, as the Prof was at medical school with the head of the vaccines unit.....but apparently that doesn’t count.

 

[screenman]

Mr Witty has said there is a shortage that will last months.

 

[SpokeyDokey]

Mr Witty has said there is a shortage that will last months.

Where did you read/hear that please?

Missed that piece of news - I'm 64 and have been wondering when I'll be 'done'.

 

[Mo1959]

They are now saying they think it will be ok to mix the vaccines so you could get one of each. Sorry, but this is really not filling me with confidence. I won’t be taking it this year when I’m not happy they really know what they are doing!

 

[roubaixtuesday]

They are now saying they think it will be ok to mix the vaccines so you could get one of each. Sorry, but this is really not filling me with confidence. I won’t be taking it this year when I’m not happy they really know what they are doing!

Fine by me. I'll have yours.

 

[vickster]

Where did you read/hear that please?

Missed that piece of news - I'm 64 and have been wondering when I'll be 'done'.

It was a BBC online headline yesterday, seems to have gone now

 

[Mo1959]

Fine by me. I'll have yours.

Fill yer boots......or your arm.