COVID Vaccine !

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vickster

Legendary Member
They are now saying they think it will be ok to mix the vaccines so you could get one of each. Sorry, but this is really not filling me with confidence. I won’t be taking it this year when I’m not happy they really know what they are doing!
Who is saying?
 

Mo1959

Legendary Member
 

roubaixtuesday

self serving virtue signaller
They are now saying they think it will be ok to mix the vaccines so you could get one of each. Sorry, but this is really not filling me with confidence. I won’t be taking it this year when I’m not happy they really know what they are doing!

On a less flippant note, this policy is a response to what is now a catastrophic situation for UK public health.

We're faced with an absolute emergency, and I don't think it's realised just how bad things are.

The rate of increase of the new strain is now ahead of any feasible vaccination programme. Thus, any vaccinations, even if slightly less effective, will directly save lives. At a very rough guess, the proposed change in approach might save 100,000 souls. Perhaps many more if our health service is completely overwhelmed. It's that bad.

Scientifically, all these vaccines work in a very similar way, by tricking the body into making the surface spike protein. So you can reasonably expect a second dose from any of the vaccines to boost immunity in a similar way. Of course that's not absolutely certain until tested.

The protection in the short term from a single dose looks very good. The second dose is required more for long term immune memory.

Alongside the vaccination, the govt needs to get out of denial and impose a strict national lockdown. The emergency measures on vaccination need an emergency response across the board to go with them.

Finally, sorry that my first response was rather grumpy. My middle son has tested positive and the whole household is now apprehensively in isolation.
 

SpokeyDokey

68, & my GP says I will officially be old at 70!
Moderator
On a less flippant note, this policy is a response to what is now a catastrophic situation for UK public health.

We're faced with an absolute emergency, and I don't think it's realised just how bad things are.

The rate of increase of the new strain is now ahead of any feasible vaccination programme. Thus, any vaccinations, even if slightly less effective, will directly save lives. At a very rough guess, the proposed change in approach might save 100,000 souls. Perhaps many more if our health service is completely overwhelmed. It's that bad.

Scientifically, all these vaccines work in a very similar way, by tricking the body into making the surface spike protein. So you can reasonably expect a second dose from any of the vaccines to boost immunity in a similar way. Of course that's not absolutely certain until tested.

The protection in the short term from a single dose looks very good. The second dose is required more for long term immune memory.

Alongside the vaccination, the govt needs to get out of denial and impose a strict national lockdown. The emergency measures on vaccination need an emergency response across the board to go with them.

Finally, sorry that my first response was rather grumpy. My middle son has tested positive and the whole household is now apprehensively in isolation.

Sorry to hear about your son. :sad:
 

MrGrumpy

Huge Member
Location
Fly Fifer
I need to stay of Twitter , too many nut jobs. Who are convinced this virus is the great reset. Governments out to reduce the population of the world and that it’s all to do with Bill Gates :whistle: .
 

roubaixtuesday

self serving virtue signaller
I need to stay of Twitter , too many nut jobs. Who are convinced this virus is the great reset. Governments out to reduce the population of the world and that it’s all to do with Bill Gates :whistle: .

I know, idiots, right?

It's Bezos who's running the show. Gates is so last millennium.
 
I'll be the first to admit that I have certain intellectual shortfalls, and I'm certainly neither an immunologist nor a virologist.

Hopefully someone on here knows better than I do, so I'm going to phrase it as a question rather than a hypothesis.

- Does messing with vaccination schedules and possibly mixing different ones risk a weakened - but stronger than if unvaccinated - immune response that doesn't quite eliminate the virus in hosts, and that those virus cells that survive the initial immune response would be more likely to be selected under Darwinian selection?

By doing this, are we this risking the rise of a new, more resistant strain?

I know that unlike antibiotics and bacteria, the vaccine doesn't directly attack the virus cells, it trains the immune response to do so, so I am happy to accept that the antibiotic resistance model doesn't apply and that I am probably wrong here.
 
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roubaixtuesday

self serving virtue signaller
I'll be the first to admit that I have certain intellectual shortfalls, and I'm certainly neither an immunologist nor a virologist.

Hopefully someone on here knows better than I do, so I'm going to phrase it as a question rather than a hypothesis.

- Does messing with vaccination schedules and possibly mixing different ones risk a weakened - but stronger than if unvaccinated - immune response that doesn't quite eliminate the virus in hosts, and that those virus cells that survive the initial immune response would be more likely to be selected under Darwinian selection?

By doing this, are we this risking the rise of a new, more resistant strain?

I know that unlike antibiotics and bacteria, the vaccine doesn't directly attack the virus cells, it trains the immune response to do so, so I am happy to accept that the antibiotic resistance model doesn't apply and that I am probably wrong here.

You're right in principle, though nobody knows how likely this is in reality.


View: https://mobile.twitter.com/kearnsneuro/status/1345150320205324288


Incidentally, viruses come as virions rather than cells.

https://www.britannica.com/science/virion
 
OP
OP
kingrollo

kingrollo

Guru
Distribution update of the Oxford variant from the Beeb, ready to go from Monday:

https://www.bbc.co.uk/news/av/uk-55515831

Presumably we should start seeing a significant dent in the number of deaths each day quite quickly as the initial vaccination targets are groups that have suffered disproportionately more than others.

Does your hope factor in the new variant (covid 20 !) - which has been reported to spread even under T4 restrictions.
 
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