COVID Vaccine !

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Location
London
According to JVT this evening the answer is "not necessarily"
can you say more/give me a link?
 

mjr

Comfy armchair to one person & a plank to the next
Risks are lower in the villages, higher in the cities. Where would you put your resources?
Lower, not zero, and I still doubt there are huge differences between medium towns and small cities. I would put resources in the Primary care and pharmacies, same as who handles the flu vaccines, not waste effort setting up a new vaccination network.
 

mjr

Comfy armchair to one person & a plank to the next
Perhaps apply for a job in vaccine logistics, you sound experienced.
About as qualified as @lane I suspect, if lane has some Operations Research training.

I may do better if I befriend an MP and bid for setting up a new vaccination network but how farking sick do you have to be to profiteer off this crisis?
 

roubaixtuesday

self serving virtue signaller
can you say more/give me a link?

You can never be absolutely definitive about the *relative* efficacy of two treatments unless they are directly compared had to head in the same trial.

The endpoints (definition of what constitutes a positive) were I think different.

You can read the Oxford trial paper here

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32661-1/fulltext

And the Pfizer one here.

https://www.google.com/url?sa=t&sou...FjACegQICxAB&usg=AOvVaw1F_b9rk3lgpqOKNSqtA_Q_
 

lane

Veteran
About as qualified as @lane I suspect, if lane has some Operations Research training.

I may do better if I befriend an MP and bid for setting up a new vaccination network but how farking sick do you have to be to profiteer off this crisis?

I am not qualified, nor do I have any interest in setting up a new vaccination network. Nor do I think it is necessary.
 
Location
London
It was on the PM briefing you can view on iPlayer. Basically he said although the Oxford vaccine had lower quoted headline efficacy the starting point was not the same so you are comparing apples with pears.
Thanks for the reply lane, but, sorry, don't understand.will try to search out.
 
Location
London
You can never be absolutely definitive about the *relative* efficacy of two treatments unless they are directly compared had to head in the same trial.

The endpoints (definition of what constitutes a positive) were I think different.

You can read the Oxford trial paper here

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32661-1/fulltext

And the Pfizer one here.

https://www.google.com/url?sa=t&sou...FjACegQICxAB&usg=AOvVaw1F_b9rk3lgpqOKNSqtA_Q_
Thanks but fear they will be beyond me. O level sciences only.
Thanks again for the reply though.
 

lane

Veteran
As far as I understand when they decide if the vaccine works or not with an individual they need some objective criteria to make the judgement. I think Oxford and Pfizer had different criteria so there results are not comparable with each other.

Just come across a clip online an interview with the Oxford professor and he said that it might not work well against the South African mutation "that has left us a bit exposed" which sounds a bit worrying.
 

SpokeyDokey

68, & my GP says I will officially be old at 70!
Moderator
Thanks for the reply lane, but, sorry, don't understand.will try to search out.

Basically, JVT was being rather pointed towards the Media who have an obsession with comparatives: witness the tables published by eg BBC re relative effectiveness of the various vaccines authorised by either the UK or other countries.

He said that they were of little value (paraphrasing) due to the different start and endpoints of the trials relating to each different vaccine. That was my take FWIW.

Apologies if I have not understood your 'don't understand' in that it may not have been regarding this point.
 
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