As long as you don't scuff the saddle or the hoods, no reason why not. But for general maintenance and chain cleaning it shouldn't be necessary. You can do that perfectly well with the bike the right way up.
I've put a cork in the top of my seat tube to stop this very thing from happening.Hummm. I was told that all high cadence would drain out of the seat tube, making it slower
My homeopath told me that inverting a bicycle can disrupt its natural magnetic field.... which can lead on to all sorts of problems such as an increased chance of speed wobble, rickety cornering and an increased risk of static interference on wireless devices such as cycle computers, smart phones and GPS units.
Not to mention all the air going to the top of the tyre, so when you put it the right way up they look flat. My tyres are only ever flat at the bottom.Hummm. I was told that all high cadence would drain out of the seat tube, making it slower
Purists may - no, will - disagree but it's never done any harm to any of my bikes. Some protection for the brake hoods and saddle might help prevent stains and scuffs.