The problem with sealant in thin-walled tyres and equally thin-walled tubes is that the high pressure of road tyres just blasts the sealant out without it having a proper chance to congeal. In MTB tyres on the other hand, it works reasonably well. The relative thickness of the tyre and the much, much lower pressure give plenty of purchase to the little granules in the sealant and gives the latex a little bit of time to congeal.
Further, even if your tyre does seal and you then use CO2 to inflate the tyre, it is ruined. The CO2 changes the pH of the suspension (usually an ammonia solution and water) which makes the latex precipitate out of the emulsion and ball up. This leaves the tube with a hard ball of latex and a thin useless and inert soup sloshing through the rest of the tyre that gives you the false impression that you still have some sealant in there.