Deadly Drink
A rich old man has died. After his death, his children are surprised to learn that he has left all of his money to his eldest son James, ignoring his other children, who hated him.
The funeral is a day or two later, and the other sons and daughters have decided to kill James and take the inheritance. Since his father's death, James has taken to drinking, and they know that, at the wake, he's going to be gulping down the liquor like it was nectar of the gods. So they decide to poison the drinks. One of the other sons, tends the bar, and gets the poison all ready.
So when James comes up, crying and depressed, and orders a scotch on the rocks. William serves him one, and he chugs it down in two seconds. "Give me another." William gives him a second glass of scotch, which he also drinks in a matter of moments. The other siblings are puzzled...the poison is fast-acting; James should be convulsing on the floor and retching his guts out.
Finally, fifteen minutes later, a rather inebriated and very much alive James orders one last glass of scotch, but as William hands it to him, he changes his mind and leaves, sobbing. The other siblings come over to William, and wonder what's going on. They talk about what could have gone wrong for a few minutes, and figure the poison's harmless. So William sips the drink he poured for James, and is pronounced DOA thirty minutes later.
Why did James live? (He had no immunity to the poison, he didn't know it was coming, and the poison was obviously deadly.)