COVID Vaccine !

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Michel tweeted on Tuesday night: “Glad if the UK reaction leads to more transparency and increased exports to EU and [other] countries. Different ways of imposing bans or restrictions on vaccines/medicines.”
Saying 'I was wrong' is so hard to do.
It also bringing the UK in to a spat the EU has with AZ. AZ are the exporter and they will do so based on their contracts, the EU hasn't exported any, AZ and Pfizer have, again based on the contracts they entered in to.
 
All I can say after being AZd a couple of weeks ago is that I still hate windows with a passion, so the nanobots seem to be as capable as windows 3.1. Now get off m'lawn you kids.
You must have gotten the linux version. Good luck playing audio through bluetooth.
 

Ajax Bay

Guru
Location
East Devon
This report (about half way down the page) back in January, referred to the Wrexham plant producing 150,000 phials a day. At six doses per phial that's 900,000 jabs. The figures I have seen don't get anywhere near that number being vaccinated everyday, even with (say) 10% wastage. The peak was at the end of January/early February.
Well done for finding that Business Live article:
The factories making Oxford-AstraZeneca, Pfizer-BioNTech and other Covid-19 vaccine in the UK
Oxford-AZ CP Pharma's Wrexham plant now has the capacity to produce (finish) about 800,000 doses a day and these are all the Oxford-AZ variety. The vaccine is actually made in England in Oxford and Keele (there's also a factory in the Netherlands). In February about 50% of the Wrexham production was exported, including to the EU. This percentage has dropped this month as the supply to UK has been ramped up. We will see 500,000+ doses overall per day being administered in UK from 14 Mar onwards so this will take more of the capacity, for several months. Most of the first jabs mid-March onwards will be Oxford-AZ. And increasing amounts will be needed for second jabs (from Easter onwards).
Oxford-AZ vaccine production is increasingly international.
Pfizer-BioNTech Nearly all the UK's Pfizer supply (e.g. from Germany (Marburg)/Belgium(Puurs)) will be used for second jabs from now on. As a contingency (to be exercised if the current under 18 trials fail), some Pfizer supply (not before August) might be earmarked for 16 and 17 year olds.
In UK the Croda plant outside Snaith (Yorkshire) has been producing/supplying four component excipients/lipids for the Pfizer/BioNTech vaccine - these have been separately listed as: [maybe worth a read @classic33 ?]
  • ALC-0315 = (4-hydroxybutyl) azanediyl)bis (hexane-6,1-diyl)bis(2-hexyldecanoate)
  • ALC-0159 = 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide
  • 1,2-Distearoyl-sn-glycero-3-phosphocholine
  • cholesterol
There has been no report of any UK export 'ban' being placed on the export of these vaccine 'components' which need to go to the continent for the manufacture of the final vaccine (and then fill&finish).
Moderna From now on (mid March) some people's first jab will be the Moderna mRNA vaccine - perhaps 50,000 a day average, and from early June their second jab of Moderna.
Novavax The Novavax vaccine will be manufactured near Middleborough (Yorks), from April (Phase 3 trial successfully complete, so hopefully getting the MHRA 'OK' in April too).
Valneva The French Biotech firm's UK plant in Livingston (Scotland) will make the UK's supply of this vaccine which has yet to complete its Phase 1/2 trials (so still early days).
Janssen UK supply (idc) to be manufactured in Belgium and fill/finish at Sanofi's Marcy l'Etoile plant (France). Vaccine already being rolled out in USA and Canada.
 
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lane

Veteran
Yes also have a couple of relatives who had AZ suffered - one quite poorly got a couple of days - so will see.
 

mjr

Comfy armchair to one person & a plank to the next
Well done for finding that Business Live article:
The factories making Oxford-AstraZeneca, Pfizer-BioNTech and other Covid-19 vaccine in the UK
[...] In February about 50% of the Wrexham production was exported, including to the EU.
That's not in that article, is it? Where did you see it?

Novavax The Novavax vaccine will be manufactured near Middleborough (Yorks), from April (Phase 3 trial successfully complete, so hopefully getting the MHRA 'OK' in April too).
Valneva The French Biotech firm's UK plant in Livingston (Scotland) will make the UK's supply of this vaccine which has yet to complete its Phase 1/2 trials (so still early days).
Neither of those are yet approved anywhere, so no test of exporting there.
 

fossyant

Ride It Like You Stole It!
Location
South Manchester
PS both my two kids are up for it. Lets them get back to normal sooner, like socialising.

No pressure from us. Daughter will be far down the line, but she'd prefer a jab to being poked up the nose twice a week for college.
 

Ajax Bay

Guru
Location
East Devon
The JCVI have advised that people experiencing homelessness, including those sleeping rough, should be prioritised for the coronavirus (COVID-19) vaccine citing heightened risks and a likelihood of health conditions and therefore poorer outcomes if they catch the disease.
Adults in these circumstances will therefore be offered a vaccine immediately (alongside priority group 6).
There's also suggested flexibility with regard to second doses, as calling people back 12 weeks later is recognised as a challenge.
Last week in Manchester, Urban Village (a primary healthcare practice with a dedicated service for homeless people) decided its homeless patients all fell into priority group 6 – anyone "aged 16 to 64 with underlying health conditions". The then guidance allowed some flexibility in vaccine deployment to mitigate health inequalities, “such as might occur in relation to access to healthcare and ethnicity”.
 
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mjr

Comfy armchair to one person & a plank to the next
Vaccine news off TV this morning:

USA President Biden has announced general availability of vaccines from 1st May, with the aim being to declare independence from the virus by 4th July. https://www.krtv.com/news/national/...ines-available-to-all-adults-by-may-1-reports

Norway, Denmark and Iceland are suspending use of OxAZ while some deaths are investigated. EMA has advised continuing use during the investigation because the evidence suggests the benefits still outweigh the risks. https://www.euronews.com/2021/03/11...tions-as-a-precaution-after-blood-clot-report
 

Ajax Bay

Guru
Location
East Devon
the aim being to declare independence from the virus by 4th July
Politicians, eh? They can offer the dream. Feasible? See below.
USA have vaccinated 98M; 54M in the last month and the weeky rate seems pretty steady (13M).
USA population is 331M, so over 16s and @ 80% acceptance = 214M to give two doses to: 428M doses required.
98M so far. 330M to go at 13M per week = 6 months. To crack it by 4 July they'll need to ramp up quickly to over 19M a week.
 
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