Ah for the Carbon bike - just get it, you won't be disappointed. The SL5 has the isospeed system which sounds like a bit of a gimmick but it does smooth out small bumps in the road nicely, it's definitely noticeable and makes the ride much more comfortable - really good for an endurance focused bike. I'd go for the SL5 over the SL4 as 105 is much better than Tiagra shifting wise and the 105 hydraulics brakes are first class. Also the SL5 has a better gear range so go figure.
If you want to ride over winter then get some mudguards fitted by the shop - the Bontrager NCS mudguards work very well with the Domane as to be expected from the same brand and I'd budget a bit of money for replacing the tyres as @steve292 says the stock tyres are OK but not brilliant - they lack great puncture protection and are a bit heavy.
Stock wheels have always been OK for me from Trek - and I'm a fairly heavy rider - but if you want to upgrade later this is where I'd start.
Overall I'd suggest getting down to your local Trek dealer and organising a test ride - if you've had your eye on it for a while which it seems like, then that's the only way to confirm whether it's the bike for you. You could always buy a cheaper or lighter bike online but you'll always be left wondering....
Edit to add: White is the only colour I'd get the SL5 in
Thanks for your advice. I'm tempted to get a bike before winter really kicks in and get a turbo trainer and stick it on there for the winter while I punish my hybrid that I have just bought mudguards for on the commute. Then just get the nice bike outside on decent weather weekends until spring.