What Mickle writes is correct, in very simple terms, the hub will twist within the wheel, initial result, not so much of the force you put into the pedals will be transferred to making you go forwards, and after a short while, the wheel will collapse. I used to use a radially spoked wheel on the front for racing on the track, and I sometimes used the same wheel for hill climbs, but not much use for normal riding, very rigid, and not really designed for your average road surface.