Just to add to others, keeping them pumped up close to the max recommended on the tyre really helps. I had no clue a few yrs back but a few punctures when I first got my road bike forced me into some practice and it's a fairly routine job now. I just carry a spare tube or 2, tyre levers and some Co2 cartridges/pump in my pocket or saddle pack. For keep the tyres pumped up a track pump is a sound investment.