Bikefit or at the very least a saddle fit which can just mean measuring your sit bones. I had saddle sores with several different saddles then found out I needed a wider one. Now having done a few hundred KMs on a Fizik Aliante problem solved for me, but its all very personal in the saddle department...
The Aliante, having read posts on the internet and advise in general is better when it is tilted back more, not forward. Tilting forward is likely to put more weight on your sit bones whereas tilting back brings the weight further forward, its all a balancing act and very personal....
Also it can take a few 100 KMs to break in a saddle properly, this doesn't mean enduring something that is downright painful but an hour usually doesn't give a long term indication...