I think there is between 1 and 2 mm between tyre and guard on my Defy pictured with 25mm tyres on it. Bike stays reasonably clean and although I would prefer to have the safety aspect of the snap on(off?) fixings of the SKS guards, these don't seem to pick up much crap at all (probably helps sweep detritus off of the tyre tbh)
As they fit to the brake\frame\fork attachment, they would should fit any bike with minimal clearance. I know the old Crud Race 1's couldn't fit the Defy, but these do...not sure if the 2nd revision of the Crud guards do, but in any case these look like an option for the clearance challenged.
So what are they? They are mighty close. Do you find the guards skitter on the tyres over rough surfaces?
Although the guards on my old Dawes Audax do skitter and the clearance is too close for my liking, I want to experiment with gluing a crud catcher at the bottom of the front guard. I will epoxy a piece of plasticard next to the flap at right angle (probably). The card may be slightly curved to the tyre profile, but the idea is that most objects will be thrown up centrally, where this device will hopefully deflect them from any further travel upwards. It won't deal with tree branches obviously, but stones won't get a look any further.