Stem orientation, flipped or slammed is a personal thing surely, different for everyone, a compromise between aero and comfort..
I talked about my peak, 18 mph averages (which compared to some are...modest) but I was doing that on a C2C Bianchi with a flipped stem for comfort. Add in the taller head tube, things weren't even remotely set up for pure speed. That said, my back wouldn't take a crunched up body position so I just used to try to be as aero as possible when circumstances allowed, mixing it with using all other contact points for comfort when needed. Your body will soon tell you when it's set up too aggressively.