Coronavirus outbreak

[Joey Shabadoo]

Doing the rounds of social media, no idea if true -



The Health Service Journal has delivered the most positive scoop of the week, revealing NHS England’s draft plan to roll out Covid vaccines to all adults in England from January, and have all over-18s in England who want one vaccinated by April. Each vaccination requires two doses, taken 28 days apart. The NHS expects to deliver 7 million doses to 3.5 million people in December alone, followed by 4-5 million more every single week from January. The moonshot plan is to deliver 88.5 million vaccination doses – to over 44 million people – all by the end of April. The rollout timetable is as follows:

Care home residents and staff, healthcare workers – from the beginning of December;
Ages 80 plus – from mid-December;
Everyone aged 70-80 – from late December;
Everyone aged 65-70 – from early January;
All high and moderate risk under 65s – from early January;
Everyone aged 50-65 – from mid-January; and
Everyone aged 18-50 – from late January; but with the bulk of this group vaccinated during March.

 

[tom73]

Doing the rounds of social media, no idea if true -



The Health Service Journal has delivered the most positive scoop of the week, revealing NHS England’s draft plan to roll out Covid vaccines to all adults in England from January, and have all over-18s in England who want one vaccinated by April. Each vaccination requires two doses, taken 28 days apart. The NHS expects to deliver 7 million doses to 3.5 million people in December alone, followed by 4-5 million more every single week from January. The moonshot plan is to deliver 88.5 million vaccination doses – to over 44 million people – all by the end of April. The rollout timetable is as follows:

Care home residents and staff, healthcare workers – from the beginning of December;
Ages 80 plus – from mid-December;
Everyone aged 70-80 – from late December;
Everyone aged 65-70 – from early January;
All high and moderate risk under 65s – from early January;
Everyone aged 50-65 – from mid-January; and
Everyone aged 18-50 – from late January; but with the bulk of this group vaccinated during March.

Basically yes that is the plan and how the government are painting it. But all the nice things like just how to do it, how to get the supply quick enough. Who is going to do all the running round or just how primary care is going to still do everything else and jab everyone at the same time. Are of course missing so it's more a statement than a plan. It's also different to the contact the GP's signed only the week before.

 

[tom73]

Boris said it would be over by Christmas and his winter covid plan looks to be more of him hell bent on it being over come what.
Then it has to do with public health sadly for many more it will be all over for good.
Handing out rapid tests as sweets is no plan at all you can't keep having cake and eating it.

 

[Ajax Bay]

Boris said it would be over by Christmas

Fact check: The PM (@ abouth 1550) specifically denied that "it would be over by Christmas" in his statement.
Which cake is being eaten, please?
You have to give due plaudits to the speech writers: "Christmas - 'Tis the season to be jolly . . . careful." Though our journalist PM no doubt has an eye for the sound bite himself.

 

[mjr]

Boris's statement to the House: https://www.gov.uk/government/speeches/pm-statement-on-covid-19-winter-plan-23-november-2020

Pretty much as leaked: lockdown will end in tiers next Wednesday. Collective bike worship may resume, in groups of six max. Tier 1 will be work from home if possible, fairly low restriction AFAICT. Tier 2 will shut pubs/bars - not sure what else. Tier 3 is lockdown-lite again. No regional variations will be negotiated. Who suffers what should be announced on Thursday. His stupid "Give Covid for Christmas" plan is still expected, but details TBC later. Then some wibble about testing and vaccines and more poundshop-Churchill words.

All rather unedifying IMO. I don't think Tiers 1 and 2 will achieve much and even Tier 3 isn't looking like it'll be that effective, if the R number hasn't dropped in several regions during this lockdown anyway. He seems to be dithering and delaying on tackling education and workplace transmission, while pressing on blindly with his "Give Covid for Christmas" plan to try to get more "Boris Saves Christmas" headlines.

 

[mjr]

Handing out rapid tests as sweets is no plan at all you can't keep having cake and eating it.

Oh but you can:

View: https://twitter.com/TheBrexitComic/status/1143402544691130368

 

[classic33]

I don't think emergency use approval is predicated on warp speed involvement.

It's a defined regulatory pathway, and they wouldn't delay a vaccine because if the funding route, I think?

Could be wrong.

[Edit: and it's only relevant to US approval anyway]

It speeds up the process of getting the vaccine, in this case, through the testing process. Still being tested in October, in use in December of the same year.

Do you reckon they'll make a seperate one for use outside of America, or that the EUA will not be used to allow use overseas.

 

[roubaixtuesday]

It speeds up the process of getting the vaccine, in this case, through the testing process. Still being tested in October, in use in December of the same year.

Do you reckon they'll make a seperate one for use outside of America, or that the EUA will not be used to allow use overseas.

The EUA is a US regulatory process.

I'm not sure of the equivalent European authorisation, but there is one, and I'm sure the companies will be applying for it (it'll be pre agreed with the regulator that this will be how it should happen).

The regulator decides if the data package supplied justifies approval in their own jurisdiction under the EUA or interim approval, or whatever it's called, and will define the full package of data required for routine approval. That'll be all the follow up data for the current trials, and possibly further trials too.

So basically, it's down to the regulator (FDA, EMA, MHRA) not the company or government, and is done on with each regulator separately. Many jurisdictions follow EU lead.

 

[classic33]

The EUA is a US regulatory process.

I'm not sure of the equivalent European authorisation, but there is one, and I'm sure the companies will be applying for it (it'll be pre agreed with the regulator that this will be how it should happen).

The regulator decides if the data package supplied justifies approval in their own jurisdiction under the EUA or interim approval, or whatever it's called, and will define the full package of data required for routine approval. That'll be all the follow up data for the current trials, and possibly further trials too.

So basically, it's down to the regulator (FDA, EMA, MHRA) not the company or government, and is done on with each regulator separately. Many jurisdictions follow EU lead.

"In a pandemic, these sequential studies can be shortened and partially overlapped but it is important to follow thousands of vaccinated people for several months before clearing the vaccine for general use."
https://coronavirusexplained.ukri.org/en/article/vdt0005/

You"ll be waiting the several months that before accepting, I take it.

 

[roubaixtuesday]

"In a pandemic, these sequential studies can be shortened and partially overlapped but it is important to follow thousands of vaccinated people for several months before clearing the vaccine for general use."
https://coronavirusexplained.ukri.org/en/article/vdt0005/

You"ll be waiting the several months that before accepting, I take it.

You've lost me, sorry? There is safety data in the regulatory files being submitted. I think Pfizer said they needed 10,000 people for a minimum of two months from the phase 3, I assume the others have similar or identical requirements.

 

[classic33]

You've lost me, sorry? There is safety data in the regulatory files being submitted. I think Pfizer said they needed 10,000 people for a minimum of two months from the phase 3, I assume the others have similar or identical requirements.

Pfizer are not part of Operation Warp Speed.

Just pointing out what the EUA will allow. Two months from testing still taking place to use.

Once given that EUA elsewhere, do you seriously expect those companies granted one, will not use it to back up use of their product elsewhere.

 

[roubaixtuesday]

Once given that EUA elsewhere, do you seriously expect those companies granted one, will not use it to back up use of their product elsewhere.

Not sure what you mean? The EUA in the US has no direct impact on other jurisdictions, and it's not uncommon for different regulators to take a different view.

Still no idea what the link to "Warp Speed" is.

 

[Unkraut]

There continue to be demonstrations against the corona restrictions by the semi-untranslatable Querdenker - thinking outside the box, but contrarians or mavericks might be better words. Now more malcontents than those with genuine grievances at the effects of lockdowns.

An 11 year old girl compared the fact she would have to celebrate her birthday secretly to Anne Frank. Blatant abuse of a child for political purposes, and the public prosecutor looked into it but it is not illegal. (It is illegal to deny or play down the holocaust.)

This has been followed by a woman in the same grouping comparing herself to Sophie Scholl, who was executed by the Nazis for spreading anti-Nazi leaflets as part of a resistance group during the war.

The mentality behind this beggars belief, but I have seen it in perhaps not quite so blatant form amongst the wail brigade who think they are hard done by if they have to wear a mask.

 

[Joey Shabadoo]

There continue to be demonstrations against the corona restrictions by the semi-untranslatable Querdenker - thinking outside the box, but contrarians or mavericks might be better words. Now more malcontents than those with genuine grievances at the effects of lockdowns.

An 11 year old girl compared the fact she would have to celebrate her birthday secretly to Anne Frank. Blatant abuse of a child for political purposes, and the public prosecutor looked into it but it is not illegal. (It is illegal to deny or play down the holocaust.)

This has been followed by a woman in the same grouping comparing herself to Sophie Scholl, who was executed by the Nazis for spreading anti-Nazi leaflets as part of a resistance group during the war.

The mentality behind this beggars belief, but I have seen it in perhaps not quite so blatant form amongst the wail brigade who think they are hard done by if they have to wear a mask.

There was a burger chain in America who introduced a 1/3 quarter pounder burger to compete against McDonald's 1/4 pounder. It flopped because people thought the McDonald's burger was bigger. 4 is bigger than 3, right?

It's because of this I no longer get surprised at the utter stupidity that some people display.

 

[rockyroller]

& hospital workers says that ppl dying (& who have died) think/thought they weren't dying & it wasn't covid ...