System weight and tyre width for me is the same (but with Conti GP4000S2 28-622 - I have a few left).
50psi on the front is rather low and you risk snake bites, imho: the tubes are not made of 'gatorskin'.
YMMV
The graph below is from the BQ article by the famous Jan Heine (2006) (attached).
Having had a significant off (ICU etc) fast downhill bitd I add 5psi to the values shown. This also means if I haven't recently (ie this week) checked pressures I can be confident that there'll still be sufficient pressure in the front tyre to be safe.
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