Hi Montage...
It takes one minute to place the bike into the turbo (on a Cycleops Mag). I dont go hell for leather on mine, more just a steady pace for keeping myself in some kind of condition. For that reason, i can use mine in the house, placed on a towel, in front of the tv, with drinks etc neaby. Its all kind of relaxed and i can use it like that for up to two hours.
I dont use a specific tyre, just the gators on my normal bike...never done my tyres any harm. No overheating tyres, no wear or squaring off. That said, i'm very careful not to have too much pressure between the tyre and flywheel.
Beware, some turbos are reputedly noisy (i assume the cheaper ones). The Cycleops Mag is quiet, just a gentle hum, and ive even fashioned a board to divert the airflow from the fan toward me for cooling)