I don't think regional or national, or local 'bias' in teams is a problem - teams are perfectly entitled to select their squad on whichever critieria they wish, and teams that are based significantly in a particular region, nation or locality can add significantly to the variety of the peloton.
However, I think it is a problem when it is in involved in assigning places to teams for supposedly global races. Surely, no-one can pretend that Bretagne-Séché Environment is a team of either the same quality or global cycling interest as MTN-Qhubeka - and, as Rich says, those should surely be be the main considerations for WorldTour races.