the big/big combination can be problematic and it's not as efficient as the same ratio using the small chainring
I thought that but recent came across this persuasive research, suggest that avoiding large/large is not an efficiency issue (my comment: but it is probably a wear and certainly a 'nowhere to go' issue). See this extract:
"Experimental results indicated that the efficiency of the chain drive varied . . . It was found that
chain-line offset and chain lubrication have a negligible
effect on efficiency under laboratory conditions. Calculations of frictional loss resulting from offset indicate that this loss should be small compared to
those produced by other mechanisms. This was verified experimentally."
But note that more generally (and away from the large/large extreme) you're better off in the large ring as, for the same gear length, it'll be more efficient as the larger sprocket is more efficient eg 50/21 is more efficient than 34/14.
"Tests of efficiency for the derailleur type chain drive
. . . factors affecting the efficiency include the sizes of the sprockets in the drive and the tension
in the chain. It was found that larger sprockets provide more efficient transfer of power while smaller sprockets proved to be less efficient."
From: "Human Power" Number 50 Spring 2000
TECHNICAL JOURNAL OF THE IHPVA
Articles
On the efficiency of bicycle chain drives
James B. Spicer and others . . . . . . . . . . . . . . . . . . . . . . . . . 3