I've been pondering the following. I'll try to keep things general and suppose an ideal type situation to attempt to get my question across clearly. (Tough ask in my case
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Let's suppose an individual is vaccinated (topical at the moment). Let's assume that the vaccine is safe with, say, a 1 in 1 million (or whatever) chance of an unpleasant and definitely unwanted side effect. Let's further suppose that the individual in question is very unlucky and is that 1 in 1 million and has the side effect. Let's now suppose that the protective effect of the vaccine declines to zero (so that the population as a whole and our individual are set to the same biological start points as before) so that another vaccination is required (in this case the same one as before).
My question is - does our previously unlucky individual have the 1 in 1 million risk of that side effect this second time around or is the risk to the individual 100%? ie is the individual always the unlucky one in the population due to some inherent individual biological quirk?
I've tried to exclude other external influences which would certainly be present in a real world scenario to get at the essence of the pondering.
Just wondering. It would be interesting to hear from a medical scientist/doctor/biologist/vaccine expert........ Any of those on here?