Current round the world record holder Mike Hall used a disk brake bike as did at least one of the previous record holders Vin Cox. It's hard to imagine that either of them could have managed such an achievement on a bike that wasn't comfortable. On the other hand the physics of disk brakes requires a stronger fork, all the manufacturers realise this, anyone in any doubt ought to go Google. I've never ridden a bike with disk brakes, though I have tried all sorts of forks, IME the difference between the harshest and the most comfortable was less than the difference between say 25mm and 30mm tyres. So if I was going for a disk fork I'd also be looking at wider tyres.
I've just sold a disk wheel I bought a year ago to give it a try. For one reason or another I never got round to it, I realised in that year I'd ridden around 8,000 miles without ever feeling the braking I had (Vs, cantis ad DPs) wasn't good enough. That's not to say if I was starting from scratch I wouldn't consider disks. But it would be for other reasons than the need for better braking.
I'm currently Audaxing on my flat barred Rohloff bike, it's perfect for the mucky lanes and a disk brake would probably add to that. Come the better weather I'll be using a lighter faster bike that I wouldn't want to have disks on. I'd suggest you spec a bike for the sort of riding you like to do, then Audax on the most appropriate one for that ride.