I've always had a fairly high tolerance to alcohol and drank a lot. As I got older I tended to still drink quite a lot at a time, but do it much less frequently - maybe one blowout every 2 months. Over the last year I've lost a lot of weight, started cycling seriously, and I'm probably fitter than I've ever been.
I've been really surprised how much alcohol affects me now as a result, and the effects really feel quite unpleasant. I get drunk faster, recover slower, and notice the impact on my body more than ever. I notice all sorts of effects, including a resting heart rate that goes up about 5 beats the next day and a training session feels rubbish. It has reached a point that I tend to avoid it altogether or if I do go out I will alternate an alcoholic drink and a soft drink to reduce my intake. I'm also one of the first people to want to go home, where before I was almost always the last, so I guess I'm pretty much opting out of drinking.
There has been a huge increase in drinking in this country over the last 40-50 years and it is really taking its toll in health terms. Cirrhosis, mental health problems and alcohol related cancers are all increasing, as are days lost to sickness, family breakdowns, alcohol related violence, financial problems etc. All-in-all it's not a pretty picture, but many people don't want to hear it.