clinical review ...
om this perspective, clinoptilolite was evaluated in a recent trial performed on aerobically trained subjects (
Lamprecht et al., 2015). In this study, endurance-trained subjects were recruited and supplemented with a clinoptilolite/dolomite/maca-based product (Panaceo Sport®). Athletes, indeed, often report intestinal symptoms including nausea, stomach and intestinal cramps, vomiting, and diarrhea.
It seems that this detoxifying effect may have additional systemic effects. The role of clinoptilolite has been recognized in medical applications, where its usage in zootechnology and veterinary medicine has provided strong evidence on improvement of pets’ fitness and efficiency in the removal of numerous harmful substances from the organism, including radioactive elements, mycotoxins, and poisons (
Laurino and Palmieri, 2015). In addition, EDTA and clinoptilolite supplementation exerted a protective effect on the brain tissue of mice intoxicated with lead by inducing antioxidant mechanisms and greater activity levels of catalase, SOD, glutathione peroxidase, and glutathione (
Basha et al., 2013). Moreover, a study in humans showed the ability of tribomechanically micronized clinoptilolite to decrease the absorption of ingested ethanol by reducing blood alcohol levels at a dose of 5 g (
Federico et al., 2015). If the clinoptilolite-containing product dosage is lower or if it is not administered at the time of alcohol consumption, this effect may not be visible as shown by
Gandy et al. (2015) where clinoptilolite still proved highly efficient in the reduction of veisalgia symptoms and signs up to 40–50%.
In addition, clinoptilolite has interesting antioxidant, hemostatic, and anti-diarrheic properties that may be exploited in human medicine, especially as adjuvants to standard therapies (
Pavelić and Hadžija, 2003). However, the number of clinical studies with clinoptilolite materials on humans is still low,