Are you talking about the fully enclosed chain case or the simple "hockey stick" guard? I presume the former.
The back won't come off. There are a few small panels around the back of it to aid wheel removal, the main two have screws, the others slide out. At the front, the "saucer" which covers the chainwheel pops out like the lid of a paint tin. To fit, you need to remove the chain, the crank, the back wheel, put the guard in place, put the crank back on, feed a bit of stiff wire up through the guard and hook the chain and slide it back into place, put the wheel back on, joint the chain, adjust chain tension and fit all the covers. Unscrew, the bung on the top and liberally drip oil in while turning the crank to lubricate the chain.
These are an absolute bastard to fit and make it a total PITA to remove the back wheel.
On the plus side, you won't have oily trousers and you can laugh at people who moan about road dirt finding it's way on to the chain.