I use Shimano SPDs and mountain bike shoes though I ride a road bike. I find these very comfortable, easy to clip in and far easier to walk in.
For me though the main benefit is shoe fit. I have very broad feet and wouldn’t be able to comfortably wear traditional road shoes. In my experience it’s easier to find broad fitting MTB shoes and the fastenings, often laces and Velcro straps, offer plenty of adjustment.
Foot comfort should be a big part of your decision on which system to use.