Actually did exactly that with a local bike box hire company . This was there reply.
Hi, there are so many variables when it comes to bikes in boxes that it's impossible to give an accurate reply.
I can tell you that the wheels can be held in place using the installed zip ties, as well as or instead of the skewers. Also that lots of people use the QR system on bolt thru with a bit of imagination, but beyond that I can’t comment I’m afraid.
Not a definite answer but looks like it will work out someway .and at £5 rental per day it's a cheap option.